Browsing Honours Theses by Author "Brosseau, Christa L."

Now showing items 1-13 of 13

Developing a localized surface plasmon aptasensor for the early detection of acute myocardial infarction

Biton, Makatendeka (Halifax, N.S. : Saint Mary's University, 2023-04-20)

Acute myocardial infarction (AMI) is a deadly disease wherein the coronary arteries become blocked, causing irreversible death to myocardial wall tissue which can result in heart failure. Current clinical methods lack the ...
Development of a DNA-based aptasensor for rapid detection of tuberculosis

Karaballi, Reem Ahmed (Halifax, N.S. : Saint Mary's University, 2013)

This project focuses on the development of a portable DNA-aptamer based biosensor, which is referred to as an aptasensor, that would aid in the diagnosis of the highly contagious disease tuberculosis. An important aspect ...
Development of a fabric-based surface-enhanced Raman spectroscopy (SERS) sensor for rapid detection of human disease biomarkers

Robinson, Ashley Megan (Halifax, N.S. : Saint Mary's University, 2014)

Currently, there is a growing demand for continuous monitoring of human disease and the development of analytical techniques capable of reliably detecting and diagnosing various illnesses. The objective of this project was ...
Development of an electrochemical aptasensor for indirect detection of target protein

Alam, Marwa Y. Shah (Halifax, N.S. : Saint Mary's University, 2015)

An aptasensor is a biosensor that makes use of aptamers as a recognition element to detect target analytes. Aptamers are sequences of single-stranded DNA (ssDNA) or RNA that can selectively bind to a wide range of target ...
Development of an electrochemical surface enhanced raman spectroscopy (EC-SERS) fabric sensor to detect cortisol for early diagnosis of post-traumatic stress disorder

Anand, Jaskaran Singh (Halifax, N.S. : Saint Mary's University, 2022-04-27)

Early diagnosis of Post-Traumatic Stress Disorder (PTSD) is challenging. Its prevalence rate in Canada is 9.2%. Experiencing stress for a sustained period can lead to a prolonged release of cortisol that causes negative ...
Development of an electrochemical surface-enhanced raman spectroscopy aptasensor for the early detection of acute myocardial infarction

Julien, Sam Michael (Halifax, N.S. : Saint Mary's University, 2022-04-20)

A common cardiovascular disease is acute myocardial infarction (AMI), which is characterized as an ischemic event within the myocardium that results in irreparable damage to the heart. Unfortunately, current clinical ...
Development of an electrochemical-surface enhanced Raman spectroscopic (EC-SERS) sensor for bacterial screening

Lynk, Taylor Paige (Halifax, N.S. : Saint Mary's University, 2018)

The lack of efficiency of current methods for bacterial screening has prompted an increasing interest in developing a cost-effective, rapid and sensitive alternative for applications in all sectors of society. This project ...
Exploration of surface plasmon-assisted catalysis (SPAC) as a new route for heterogeneous catalysis

Davidson, Melanie Dawn (Halifax, N.S. : Saint Mary's University, 2017)

Plasmonics is the study of the interactions between the free electrons of a metal, and the electric field component of light. In the presence of the oscillating electronic field, the free electrons in the metal oscillate ...
An exploration of thermomechanical softwood pulp for N95 respiratory mask production

McLeod, Kaleigh Elizabeth Rita (Halifax, N.S. : Saint Mary's University, 2021)

The COVID-19 pandemic has highlighted supply chain issues for personal protective equipment (PPE) in Canada. In addition, many PPE products are produced from non-renewable feedstocks. Wood pulp is an abundant and renewable ...
Fabrication of multidimensional surface-enhanced Raman spectroscopy (SERS) substrates using bioscaffolds

St. Marie, Gaius (Halifax, N.S. : Saint Mary's University, 2019)

Plasmonics is the field of research which explores the unique optical and electronic effects observed when certain nanoscale metals interact with light. Plasmonic nanostructures that are uniform in size and shape are highly ...
Investigation of a yellow lake pigment using 2D-LC and EC-SERS

Eisnor, Maddison Margaret (Halifax, N.S. : Saint Mary's University, 2020)

The identification of natural organic pigments is fundamental for the conservation, preservation, and historical interpretation of artwork. Natural pigments, derived from plant and insect sources, can experience fading and ...
Langmuir-Blodgett deposition of functionalized AuNRs towards multidimensional LSPR sensing

MacMillan, Presley Sarah (Halifax, N.S. : Saint Mary's University, 2017)

Understanding the surface plasmon resonance properties of gold nanorods (AuNRs) and exploring their sensitivity has attracted much attention due to the potential applications in the biomedical field; including detection ...
The synthesis, characterization and modification of gold nanoparticles for use in SERS-based COVID-19 antibody testing

MacInnis, Marissa J. (Halifax, N.S. : Saint Mary's University, 2021)

The current COVID-19 pandemic has highlighted a need for rapid, point-of-care (POC) antibody testing. Antibody testing would allow for a determination of which members of the population have already been infected with the ...