Browsing by Author "Doucet, Katherine Grace"

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Dacarbazine and its structural analogues : systematic computational studies of the configurations, tautomers, tautomerization pathways and bimolecular nucleophilic substitution reaction mechanisms of dacarbazine : a triazene containing anti-neoplastic agent, and its structural analogues

Doucet, Katherine Grace (Halifax, N.S. : Saint Mary's University, 2007)

A monomethyltriazene is believed to be the active metabolite of triazene containing anti-neoplastic agents and is thought to methylate the O6-oxygen of guanine to form methylguanine. Methylguanine is believed to be responsible ...

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