This study analyzes the temporal and spatial distribution of satellite-observed NO2 and O3 concentrations in Edmonton, Canada, from July 2018 to June 2023. It explores the relationship of NO2 and O3 concentrations with elevation, temperature, road density, and population density. Results show higher NO2 concentrations during winter and lower in fall months; however, O3 concentrations remain relatively stable compared to NO2 during the study period. NO2 concentrations are highest in central Edmonton and lowest in surrounding suburban regions, while O3 shows higher concentrations in central and western Edmonton and lower in eastern and southern suburban areas. Higher NO2 concentrations are found on Wednesdays and lower on Sundays while O3 remains consistent throughout the week. The research methodology adopted in this study may help the scientific community understand the complex interactions between anthropogenic activities and air pollution. Furthermore, the findings may help guide urban planners and policy makers in prioritizing air pollution control in the hotspot areas identified in the study.