The Canada-France Imaging Survey (CFIS) will map the northern high Galactic latitude sky in the u-band ("CFIS-u," 10,000 deg2) and in the r-band ("CFIS-r," 5000 deg2), enabling a host of stand-alone science investigations, and providing some of the ground-based data necessary for photometric redshift determination for the Euclid mission. In this first contribution, we present the u-band component of the survey, describe the observational strategy, and discuss some first highlight results, based on approximately one-third of the final area. We show that the Galactic anticenter structure is distributed continuously along the line of sight, out to beyond , and possesses a metallicity distribution that is essentially identical to that of the outer disk sampled by APOGEE. This suggests that it is probably a buckled disk of old metal-rich stars, rather than a stream or a flare. We also discuss the future potential for CFIS-u in discovering star-forming dwarf galaxies around the Local Group, the characterization of the white dwarf and blue straggler population of the Milky Way, as well as its sensitivity to low surface brightness structures in external galaxies.